anti-XPA antibody
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation. Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.) Uniprot: ID P23025 Immunogen: xeroderma pigmentosum, complementation group A Recommended dilution: WB:1:200-1:2000;IF:1:50-1:500 Host: RabbitApplications Tested/Suitable: ELISA,WB